The active ingredient of PENEGRA is sildenafil. One tablet of the drug contains 100 mg or 50 mg of sildenafil depending on make. (in the form of sildenafil citrate)

The recommended dose of 50 mg is taken, if necessary, approximately one hour before the planned sexual intimacy.
taking into account the effectiveness and tolerability of the dose can be increased to 100 mg or reduced to 25 mg
the maximum recommended dose is 100 mg
maximum recommended frequency of application – once a day
in the elderly and patients with impaired renal or liver function, the recommended regimen is the same
It is important to note that an erection occurs only with sexual arousal. As for the mechanism of action of PENEGRA , it is to increase the amount of blood entering the penis, which helps a man to cause a natural erection. Sildenafil Citrate acts only when a man experiences a natural sexual arousal, and when sexual intercourse is completed, the penis naturally returns to a relaxed state. In other words, Sildenafil Citrate acts only on the natural mechanisms of erection.

Sildenafil Citrate is the first representative of a new group of drugs called phosphodiesterase inhibitors of the 5th type. The drug dilates the blood vessels of the penis during sexual arousal. As a result, the blood flow in the penis increases, which contributes to the onset of normal erection.

Active ingredient

The active ingredient of PENEGRA is sildenafil. One tablet of the drug contains 100 mg of sildenafil (in the form of sildenafil citrate)

Inactive components

The PENEGRA also contains the following inactive components, such as microcrystalline cellulose, calcium hydrogenphosphate (anhydrous), croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide (U171), lactose, triacetin, indigo carmine aluminum varnish (E1).


Sildenafil Citrate is intended for the treatment of men with erection disorders, also called impotence. In this condition, men do not have a normal erection, necessary for sexual intercourse.

Sildenafil Citrate acts only in response to sexual arousal. Sildenafil Citrate does not affect reproductive function.


Do not take PENEGRA if:

You have had an allergic reaction to Sildenafil Citrate or any component of the drug in the past. An allergic reaction may manifest as a rash, itching, swelling of the face or lips, shortness of breath. If you had similar symptoms, then inform your doctor;
You are taking nitrate-containing or nitrate-containing drugs to treat angina. Sildenafil Citrate can cause an undesirable increase in the action of such agents. If you are taking these drugs, tell your doctor or pharmacist.


If you suffer from any of the following conditions, then you should inform your doctor before starting PENEGRA-100:

sickle cell anemia (change in red blood cells),
leukemia (cancer of blood cells),
multiple myeloma (bone marrow cancer)
disease or deformity of the penis.
When treating drugs that affect erectile dysfunction, people with these diseases may need special precautions.

rare eye disease called retinitis pigmentosa
gastric ulcer and bleeding disorders (for example, hemophilia). In these diseases, Sildenafil Citrate appears to have an undesirable effect.
PENEGRA-100 can not be used in combination with other drugs intended for the treatment of erectile dysfunction.

Use in the elderly and patients with kidney or liver disease.

Special recommendations for the treatment of elderly people and patients with diseases of the kidneys or liver are absent. Special precautions when driving a car or machinery are not required.

Interaction with other drugs.

You should inform your doctor about all the drugs you are taking. Sildenafil Citrate may interact with certain medications. Sildenafil Citrate can cause undesirable enhancements to the action of other medicines, which are called nitric oxide donators or nitrates (they are used in the treatment of angina pectoris). If you are receiving such drugs, then taking PENEGRA-100 is prohibited!


Do not take a higher dosage pill than recommended by your doctor. You can not take more than one tablet per day. If you take more pills than you were recommended, consult your doctor immediately.

Dosing regimen

The doctor will decide at what dose you should take PENEGRA-100. For most men, it is 50 mg, but, depending on the effectiveness and tolerability of the drug, the dose can either be increased to 100 mg, or reduced to 25 mg.

PENEGRA-100 should be taken approximately 30-60 minutes before sexual intercourse. Swallow the pill whole and drink it down with a small amount of water. PENEGRA-100 can be taken no more than once a day. Sildenafil Citrate contributes to the onset of erection ONLY in the presence of sexual arousal. Spontaneous erection without erotic stimulation, it does not cause. The effect of PENEGRA-100 begins at different times in different people, but usually from 30 minutes to 1 hour after administration and lasts 4-6 hours. After a heavy meal, the effect of PENEGRA-100 may begin later. Taking alcohol can lead to temporary erectile dysfunction, so it is not recommended to use it in large quantities for maximum effect.

If taking PENEGRA-100 does not facilitate the onset of an erection or does not persist long enough to complete intercourse, you should consult a doctor.

Side effect

Like most other drugs, sildenafil citrate can cause some unwanted reactions. They are usually light or moderately pronounced and do not last long. The most common side effects are headache and flushing. Less common are digestive disorders, dizziness, nasal congestion, and vision changes (changes in the color of objects, increased brightness of the light, or blurred vision).